However, in approximately 60%—90% of patients with OP, the radiographic and CT findings are often so characteristic that they suggest the pattern of injury.
The organisation of an actin + fibrous plug immunostainings not shown within an alveolus, intermingled with lymphocytes dotted line , corresponding to organising pneumonia with prominent hyperplasia of surrounding alveolar pneumocytes arrows.
Organising pneumonia manifesting as a late
Corticosteroids are the cornerstone of therapy for OP.
IV, FH-S, PD, FCR, KT, MH, SG, H-DW, FG, SH and WS: acquisition, analyses or interpretation of data.
A single-centre prospective observational study had shown about one-quarter of post-COVID-19 pneumonia had recurring dyspnoea with radiological findings of OP where resuming corticosteroids resulted in clinical and radiological improvements.
Organizing pneumonia has been described as a pulmonary response in patients with SARS-CoV-2 pneumonia. We present the case of a patient with SARS-CoV-2 pneumonia and torpid clinical and radiological evolution in whom organizing pneumonia was documented through transbronchial biopsy.
Organizing pneumonia is a manifestation of COVID‐19 pneumonia, seen here in a patient who did not suffer from acute respiratory distress syndrome and went on to have full resolution of respiratory symptoms. The morphologic findings are typical of organizing pneumonia, characterized by loose plugs of fibromyxoid tissue.
Organizing pneumonia emerges as a late phase complication of COVID-19. Corticosteroids are standard therapy for organizing pneumonia, but the question of whether an approach with high dose corticosteroids would be beneficial for patients with organizing pneumonia secondary to COVID-19 remains to be answered.
In this article, we talk about a subgroup of patients with organizing pneumonia following COVID-19 pneumonia that could be effectively treated with systemic glucocorticoids. It is important that patients with COVID-19 pneumonia be followed-up at least three weeks after diagnosis, in order to recognize early lung damage.
We should consider organizing pneumonia as a sequela after COVID-19. TBLB is an option when the diagnosis of organizing pneumonia is difficult only from radiological and microbiological findings. Secondary organizing pneumonia after COVID-19 is also a reversible condition owing to a sufficient treatment of corticosteroids.
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